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Google's AI genome system evaluates every possible one-base change

9 September 2026 at 16:34

On Tuesday, Google announced AlphaGenome Atlas, a resource that attempts to predict the consequences of every possible single-base variant in the human genome. The human genome is about 3 billion bases long, so trying the other three DNA bases that don't appear in our reference genome means sending a total of 9 billion bases through AlphaGenome software.

AlphaGenome is designed to identify potential functions of non-coding DNA, which does not encode proteins but makes up the vast majority of the human genome. Some of this non-coding DNA is essential for controlling the activity of the protein-coding portion—it tells the cell where and when to make messenger RNAs, how to process them into mature protein-coding forms, and so on. But much of it appears to be little more than the remains of viruses and other molecular parasites.

Being able to identify the functional portion is very useful, as is having all the analysis done by a single software package. But until biologists start to use it heavily (assuming they do), it won't be clear what AlphaGenome offers beyond what we could have gotten out of its training data.

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When Workplace Emotions Spike

14 August 2026 at 09:45

If you’ve ever lost it in a meeting, or avoided your manager after an unfiltered emotional reaction, what you’ve experiences isn’t personal weakness. It’s your brain doing exactly what ADHD brains do under stress.

Whether you’re anticipating or recovering from a difficult situation at work, use the SPACE model to stay calm, regulate your emotions, and recover professionally. Remember that controlling emotions isn’t about becoming someone else; it’s about developing more skill in being who you already are.

S: Spot Your Patterns

Get ahead of the problem by recognizing triggers, such as:

  • Performance reviews
  • Activities with high-stakes visibility
  • Unclear expectations
  • Deadlines
  • Increased workload

Think about your last three emotional workplace incidents to identify your personal triggers.

[Watch: How ADHD Amplifies Emotions]

Signs of activation:

  • Increased blinking
  • Voice pitch change
  • Posture shifts
  • Muscle tension, fidgeting, pen-clicking
  • Shallow breathing
  • Feeling hotter or colder
  • Elevated heart rate
  • Irritability, defensiveness, and black-and-white thinking
  • Stomach tightness, nausea
  • Feeling an impulse to escape or hide
  • Difficulty tracking conversations

[Read: How to Keep Emotional Distress from Snowballing]

P: Pause the Escalation

All you need is 90 seconds to let a feeling pass and avoid further activation. Try these tactics to buy yourself time:

  • Bring a pen and paper to meetings. Writing gives you something to do and slows down the brain.
  • Take sips of water; swallowing taps the parasympathetic nervous system, signaling the body to calm down.
  • Roll your shoulders, adjust your posture, and press your feet to the floor.
  • Count backward from 100 by 5s.
  • Squeeze your hands together under the table.
  • Try box breathing – inhale, hold, exhale, hold again, for 4 counts each.
  • Describe the meeting room in your head (note colors, shapes, temperature, etc.).
  • Use strategic fillers:
    • “That’s a great question. Let me think about that for a moment.”
    • “Would it be helpful if I put some thoughts in writing?”

A: Act in the Moment

When you’re activated and need to do something NOW:

  • Treat yourself kindly. Instead of, “I’m so stupid; this always happens,” say, “I need a moment to collect my thoughts.”
  • Normalize tears. Say, “I’m getting emotional because this matters.” Breathe through your nose and keep talking to reduce tears.
  • Lower your voice and speak slowly and deliberately.
  • Uncross your arms and unclench your hands.
  • Focus on facts. Say, “What I’m hearing is…”
  • Maintain eye contact to steady your focus, but don’t force it.
  • Pause and revisit:
    • “I’m going to grab some water and be right back.”
    • “Can we come back to this in 15 minutes? I’ll be more productive after a quick reset.”
    • “Thank you for your patience. I am ready to continue now.”

C: Clear the Air

Perform damage control within 24 hours. Begin by considering the following:

  • Have you recovered enough to begin addressing the incident?
  • What’s the minimum viable response?
  • Avoid over-apologizing. Say: “I didn’t handle that as well as I would have liked. I take responsibility for my behavior. Here’s how I plan to address future situations.”

Consider these steps if you have formally disclosed your ADHD diagnosis.

  • Talk to your manager if the incident affected team dynamics or if your professional development is at stake.
  • Focus on solutions, not limitations. You might say, “I have ADHD and sometimes need accommodations around ___. This is what works for me…”
  • Request specific supports with timelines:
    • “Could I receive meeting agendas 24 hours in advance so I can prepare?”
    • “Could we meet weekly to discuss workload concerns before they escalate?”

E: Evolve

  • Revisit your morning routine to find new ways to reduce stress before work.
  • Implement transition rituals (e.g., At 12 p.m., I will step away from my desk for lunch. Before returning to work, I will take three deep breaths).
  • Schedule decompression time after meetings or other triggering activities.
  • Understand your sensory triggers and modify your environment (e.g., noise levels, lighting, room temperature, smells).
  • Script responses to predictable tough questions. Role play difficult conversations with trust people.
  • Remember that preparation is not a sign of weakness; it’s a strategy.
  • Continue to identify tools for your emotional regulation kit – box breathing, self-talk, etc. Practice these skills even in the absence of stress. Seek therapy for additional help in building coping skills.
  • Let time and changed behavior speak for you. Continue to gather evidence that you can handle such situations differently.

How to Control Your Emotions at Work: Next Steps

Diann Wingert is a licensed psychotherapist-turned-business-coach for neurodivergent entrepreneurs.


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UK regulator warns of "arms race" to keep up with AI use in financial services

6 July 2026 at 14:17

Regulators are in an “arms race” to keep up with the use of artificial intelligence in financial services, a senior UK official has warned, with millions of people using the technology to help them make personal finance decisions.

Sheldon Mills, an executive director at the Financial Conduct Authority, told the FT the watchdog would need greater powers to stay on top of the rapid growth of AI and urged UK authorities to review whether the use of ChatGPT, Claude, Gemini, and other large language models should be subject to their rules.

Speaking ahead of the publication on Monday of an FCA-commissioned report he has written on the impact of AI in financial services, Mills said regulators in the area would have to embrace AI themselves to keep up with the “speed, pace, and scale of change” the technology is bringing to the sector and to help “monitor, detect, and tackle the risks.”

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Trump gets OpenAI to offer US 5% stake, far lower than Sanders’ target

OpenAI CEO Sam Altman is reportedly in active talks with the Trump administration about the US potentially acquiring a 5 percent stake in the leading AI firm.

Insider sources told the Financial Times that these talks are in “early stages,” but Altman “has argued that giving the public a financial stake in the company is the best way to share the upside of AI.”

Donald Trump favors the idea, and his administration has reportedly been talking to several AI firms about the possibility. According to FT’s sources, other companies approached to share similar stakes include Google and Meta.

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The EU’s Retreat on Corporate Accountability

11 March 2026 at 15:38
The EU’s Retreat on Corporate Accountability: Growth, Imperial Extraction, and the Limits of Regulation by Alice Puerto* In the series Degrowth and Ecosocialism: the global picture In 2025, the European Union took what may prove to be a historic step backward. Under pressure from a consolidated right–far-right bloc in the European Parliament, led by the… Continue reading The EU’s Retreat on Corporate Accountability

The EU’s Retreat on Corporate Accountability

11 March 2026 at 15:38
The EU’s Retreat on Corporate Accountability: Growth, Imperial Extraction, and the Limits of Regulation by Alice Puerto* In the series Degrowth and Ecosocialism: the global picture In 2025, the European Union took what may prove to be a historic step backward. Under pressure from a consolidated right–far-right bloc in the European Parliament, led by the… Continue reading The EU’s Retreat on Corporate Accountability

How to Make Writing Emails Easier with ADHD (Part 3 of 3)

10 October 2025 at 14:02

Learn how to stop avoiding emails and make writing and sending them easier when you have ADHD — without all the second-guessing.

The post How to Make Writing Emails Easier with ADHD (Part 3 of 3) appeared first on Marla Cummins.

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